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Immune disorders

Biology • Immune System • Knowledge-Based • 5 questions

Immune disorders Knowledge-Based Download PDF

Biology · Human Body & Physiology · Biology · Immune System

5 Biology practice questions on Immune disorders. Questions that assess core concepts and understanding.

Questions

  1. 1.

    Which of the following autoimmune disorders is caused by autoantibodies directed against nicotinic acetylcholine receptors at the neuromuscular junction, leading to fluctuating skeletal muscle weakness?

    • A) Multiple sclerosis
    • B) Systemic lupus erythematosus
    • C) Myasthenia gravis
    • D) Rheumatoid arthritis
  2. 2.

    Which of the following primary immunodeficiency disorders is characterized by a congenital genetic defect that disrupts the development and function of both T lymphocytes and B lymphocytes?

    • A) X-linked agammaglobulinemia
    • B) Severe combined immunodeficiency
    • C) DiGeorge syndrome
    • D) Chronic granulomatous disease
  3. 3.

    Which of the following immune cell populations is primarily targeted and depleted by the Human Immunodeficiency Virus (HIV), leading to the profound secondary immunodeficiency characteristic of AIDS?

    • A) CD4+ helper T lymphocytes
    • B) CD8+ cytotoxic T lymphocytes
    • C) Mature naive B lymphocytes
    • D) Neutrophilic granulocytes
  4. 4.

    Which of the following events triggers the rapid release of histamine and other inflammatory mediators during an immediate (Type I) hypersensitivity reaction?

    • A) Activation of cytotoxic T lymphocytes that directly lyse allergen-coated host cells
    • B) Accumulation and deposition of circulating antigen-antibody complexes in capillary walls
    • C) Cross-linking of allergens to IgE antibodies bound to the surface of mast cells
    • D) Recruitment of memory T cells that stimulate delayed macrophage-driven inflammation
  5. 5.

    Which of the following biological mechanisms fundamentally characterizes the development of an autoimmune disorder?

    • A) Failure of immunological self-tolerance, causing lymphocytes to recognize and attack the body's own antigens
    • B) Overproduction of immunoglobulin E (IgE) antibodies that bind to mast cells in response to non-pathogenic environmental antigens
    • C) Selective destruction of CD4+ helper T cells by an infectious agent, resulting in severe acquired immunodeficiency
    • D) Genetic defects in lymphocyte development that completely prevent the maturation of functional B and T cells