Amides Knowledge-Based Practice

Questions

1. 1.

   Which of the following organic compounds is formed as the major product when butanamide is heated in the presence of phosphorus pentoxide ($\text{P}_4\text{O}_{10}$)?

   • A) Butan-1-amine
   • B) Butanoic acid
   • C) Butanenitrile
   • D) Butanal
2. 2.

   Which of the following organic compounds is formed when propanamide is treated with lithium aluminium hydride ($\text{LiAlH}_4$) in dry ether, followed by aqueous workup?

   • A) Propan-1-ol
   • B) Propan-1-amine
   • C) Propanoic acid
   • D) Propanenitrile
3. 3.

   Which of the following pairs of products is obtained from the complete acidic hydrolysis of N-methylpropanamide with aqueous hydrochloric acid?

   • A) Propanoic acid and methanol
   • B) Propanoic acid and methylammonium chloride
   • C) Propan-1-ol and methanamide
   • D) Propanoate ion and methylamine
4. 4.

   Which of the following nitrogen-containing compounds reacts with an acyl chloride to yield a tertiary amide as the major organic product?

   • A) Ammonia
   • B) A primary amine
   • C) A secondary amine
   • D) A tertiary amine
5. 5.

   Which of the following statements correctly explains why amides are significantly less basic than aliphatic amines?

   • A) The lone pair of electrons on the amide nitrogen is delocalized into the adjacent carbonyl $\pi$ system through resonance.
   • B) The amide nitrogen possesses a rigid tetrahedral geometry that physically shields its lone pair from incoming protons.
   • C) The adjacent carbonyl oxygen atom donates electron density to the nitrogen atom through strong inductive effects.
   • D) The nitrogen atom in an amide lacks a nonbonding electron pair because it participates in permanent triple bonding.

Answers and step-by-step solutions appear after you finish the test.