Central dogma Transitional Reasoning Download PDF

Questions

1. 1.

   In an experimental investigation, researchers evaluated two antimicrobial agents that target distinct stages of the central dogma in bacterial cells. Compound 1 specifically inactivates RNA polymerase, whereas Compound 2 selectively inhibits the formation of peptide bonds at the ribosome. Based on the directional flow of genetic information, which statement correctly identifies the direct molecular processes disrupted by these two compounds?

   • A) Compound 1 immediately halts DNA replication, while Compound 2 prevents the synthesis of mRNA transcripts from the DNA template.
   • B) Compound 1 prevents tRNA charging in the cytoplasm, while Compound 2 blocks the enzymatic unwinding of double-stranded DNA.
   • C) Compound 1 directly inhibits the transcription of DNA into RNA, while Compound 2 directly disrupts the translation of mRNA into a polypeptide chain.
   • D) Compound 1 disrupts post-translational folding of proteins, while Compound 2 prevents the nuclear export of mature ribosomal subunits.