Central dogma Original Scenario-Based Download PDF

Questions

1. 1.

   In an advanced biofoundry, synthetic biologists engineer an artificial organism whose gene expression strictly mirrors the canonical central dogma of molecular biology. To produce a vital protective enzyme, genetic information must flow directionally from a stable double-stranded DNA template to functional proteins. If an experimental compound completely disables the cellular machinery responsible for assembling amino acid chains at the ribosome while leaving RNA synthesis entirely unimpeded, which process continues to operate and what product accumulates in the cell?

   • A) Transcription continues to operate, resulting in the accumulation of messenger RNA transcripts.
   • B) Translation continues to operate, resulting in the accumulation of non-functional polypeptide chains.
   • C) Reverse transcription continues to operate, resulting in the direct synthesis of complementary DNA from ribosomes.
   • D) Replication continues to operate, resulting in the conversion of amino acid precursors directly into genomic DNA.