Cancer and uncontrolled cell division Original Scenario-Based Practice

Biology · Cell Communication & the Cell Cycle · Biology · Cell Cycle & Cell Division

1 Biology practice questions on Cancer and uncontrolled cell division. Questions built around original scenarios.

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  1. 1.

    In an experimental bio-dome simulating alien deep-sea hydrothermal vents, researchers engineer a strain of human tissue cells called "Hydra-X" to study extreme tissue regeneration. Surprisingly, Hydra-X continues proliferating relentlessly even when overcrowding strips the growth medium of external growth factors, completely disregarding contact inhibition and internal DNA damage signals. Which underlying cellular defect best explains why Hydra-X exhibits this hallmark phenotype of cancer cells?

    • A) Complete cessation of telomerase expression leading to rapid telomere shortening
    • B) Permanent activation of checkpoint proteins that halt the cell cycle at the G1/S boundary
    • C) Overexpression of pro-apoptotic genes triggering premature programmed cell death
    • D) Loss-of-function mutations in tumor suppressor genes coupled with hyperactive oncogenic signaling

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