Cancer and uncontrolled cell division Knowledge-Based Download PDF

Questions

1. 1.

   Which of the following statements correctly describes a cellular mechanism that contributes to uncontrolled cell division in cancer?

   • A) Tumor suppressor genes undergo gain-of-function mutations that accelerate progression through the G1 checkpoint.
   • B) Cancer cells exhibit elevated density-dependent inhibition, causing them to permanently enter the G0 resting state.
   • C) Accelerated shortening of telomeres enables cancer cells to divide indefinitely without triggering replicative senescence.
   • D) Loss-of-function mutations in tumor suppressor genes prevent cell cycle arrest, allowing damaged cells to proliferate.