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Receptors and ligands

Biology • Cell Communication • Transitional Reasoning • 1 questions

Receptors and ligands Transitional Reasoning Download PDF

Biology · Cell Communication & the Cell Cycle · Biology · Cell Communication

1 Biology practice questions on Receptors and ligands. Questions that build towards applied reasoning.

Questions

  1. 1.

    A researcher investigates the signaling mechanisms of two signaling molecules: Molecule X, a small lipid-soluble steroid, and Molecule Y, a large hydrophilic polypeptide. Prior to applying either ligand, target cells are pretreated with an impermeable compound that selectively binds to and blocks the extracellular domains of plasma membrane receptors. Based on the biochemical properties of these ligands and their corresponding receptors, which outcome will the researcher most likely observe?

    • A) Both Molecule X and Molecule Y fail to trigger their respective intracellular pathways.
    • B) Molecule Y triggers its cellular response normally, whereas Molecule X is blocked from activating its signaling cascade.
    • C) Molecule X is blocked at the cell surface, whereas Molecule Y diffuses freely into the nucleus to activate transcription.
    • D) Molecule X triggers its normal cellular response, while the signaling pathway of Molecule Y is effectively blocked.